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FDA approved imlunestrant, marketed as Inluriyo by Eli Lilly, for adults with ER-positive, HER2-negative, ESR1-mutated advanced or metastatic breast cancer following progression after at least one line of endocrine therapy.
The approval reinforces the role of mutation testing in breast-cancer treatment decisions, particularly after endocrine resistance emerges.
For oncology systems, each biomarker-linked approval adds pressure to make molecular testing timely and routine.
Why It Matters
Breast-cancer treatment is becoming more molecularly segmented, with ESR1 mutation status guiding therapy after endocrine progression.
What to Watch
Watch testing patterns, sequencing with CDK4/6 inhibitors and uptake outside academic cancer centres.
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