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FDA approved belantamab mafodotin-blmf, marketed as Blenrep, with bortezomib and dexamethasone for adults with relapsed or refractory multiple myeloma after at least two prior therapy lines.
The treatment targets BCMA, a major focus in myeloma therapy across antibody-drug conjugates, bispecifics and CAR-T approaches.
For clinicians, the approval adds another late-line combination option in a crowded but still high-need disease area.
Why It Matters
Myeloma care is being reshaped by BCMA-directed therapies and increasingly complex treatment sequencing.
What to Watch
Watch eye-toxicity monitoring, sequencing against bispecifics and CAR-T, and use outside academic centres.
Primary Sources
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